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Continued How Do I Find Out What My Cholesterol Numbers Are and What They Mean? Alberts, A. W. The effects of mevinolin on serum cholesterol levels of rabbits with endogenous hypercholesterolemia. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Hou, Z. l. Xuezhikang toxicity study. Many studies show that almonds have real health benefits too. anastrozole for christening

How should I take VYTORIN?

Studies show that statins lower the chance of a “cardiovascular event” such as a heart attack. Use is contraindicated in the setting of active liver disease. Wang LB, Qiao JJ Li YM. Clinical evaluation of Zhibituo and concentrated fish oils for treatment of hyperlipidemia.

Common side effects of simvastatin

VYTORIN does not help you lose weight. Lu, Z. Clinical trial of extract of Monascus purpureus red yeast in the treatment of hyperlipidemia. Colchicine is to be used only by the patient for whom it is prescribed. Do not share it with other people.

How to take simvastatin

Tell your doctor or dentist that you take simvastatin before you receive any medical or dental care, emergency care, or surgery. Simvastatin may need to be stopped for a few days before certain types of surgery. Though less rhythmic than other types of massage, deep tissue massage can be quite therapeutic -- relieving chronic patterns of tension and helping with muscle injuries, such as back sprain. Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.

Important information

Consuming large amounts of grapefruit juice increases serum levels of simvastatin by up to three-fold, increasing the risk of side effects. The FDA recommends that people taking statins should avoid consuming more than a quart of grapefruit juice per day. Cheng, J. T. Plasma glucose-lowering action of Hon-Chi in streptozotocin-induced diabetic rats. Horm. INR in patients who had ezetimibe added to warfarin. Wong, H. C. and Bau, Y. S. Pigmentation and Antibacterial Activity of Fast Neutron- and X-Ray-induced Strains of Monascus purpureus Went. Clinical pharmacology and therapeutics. It works by reducing the production of certain fatty substances in the body, including cholesterol. Oct. I'm getting worse. I have pins and needles attack my feet, calves fairly bad, and my hands a little bit. Last week-it became a gigantic problem. It's all over my body-and I want to throw up again. It's getting progressively worse. I'm also developing tremors in my hands and arms. My left tendon went down and is seeming to be well, but my right tendon flares up. Exercise and ice packs were helping-but It seems to have stopped progress. Does anybody have a clue about the pins and needles sensation? Mortensen SA, Leth A, Agner E, Rohde M. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Prior to treatment initiation patients should be placed on a standard cholesterol lowering diet, which should continue during treatment. Yu P, Shen Z, Sun M, et al. A clinical study of Xuezhikang on the treatment of primary hyperlipidemia. Simvastatin Oral Suspension should be considered. WEDNESDAY, March 4, 2015 HealthDay News -- Cholesterol-lowering statin drugs may significantly increase a person's risk of developing type 2 diabetes, a new study from Finland suggests. Bi JZ, Ma SZ Li YQ. Observations on the therapeutic effects of Diao Zhibituo for treatment of hyperlipidemia.

LDL levels tend to rise

Viden, I. Identification of volatile metabolites from rice fermented by the fungus Monascus purpureus. Who should not take VYTORIN? Concomitant intake of grapefruit juice and simvastatin should be avoided. To get your cholesterol down to lower your risk of cardiovascular disease your doctor may recommend, though, that you still need a statin. These powerful cholesterol-lowering medicines include and among others. The case for cholestin. Heber, D. Dietary supplement or drug? High cholesterol itself does not cause any symptoms, so many people are unaware that their are too high. Therefore, it is important to find out what your are. Lowering cholesterol levels that are too high lessens the risk for developing heart disease and reduces the chance of a or dying of heart disease, even if you already have it. What Numbers Should I Look For? phenergan

Do not share it with other people

CHILDREN younger than 10 years old; safety and effectiveness in these children have not been confirmed. Retrieved 14 January 2015. The solid line represents a relative risk of one. Experimental studies on toxicology of Xuezhikang. Antacids: May decrease the serum concentration of HMG-CoA Reductase Inhibitors. Evaluate for new-onset diabetes mellitus during therapy; if diabetes develops, continue statin therapy and encourage adherence to a heart-healthy diet, physical activity, a healthy body weight, and tobacco cessation. Do not drink large amounts of alcohol with simvastatin. This could cause unwanted effects on the liver. Tell your doctor if you have ever had any unusual or allergic reaction to simvastatin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. But studies of the drugs paint a starkly different picture. In studies where patients are randomly assigned to take a statin or a placebo pill, the rates of side effects reported by each group are nearly identical, leading many doctors to wonder if the side effects are really due to the medications or if something else, like the nocebo effect, might be at work. In the nocebo effect -- the opposite of the -- a person suffers side effects from a fake medicine. get chloroquine without insurance chloroquine

Simvastatin dosage

Yang, C. Clinical observation of the effects of xuezhikang on older primary hyperlipidemia patients. There, it is eliminated from the body. How Do Statin Drugs Work? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Chinese patients applies to other Asian patients. How Does High Cholesterol Cause Heart Disease? VYTORIN works to reduce your cholesterol in two ways. Higher systemic exposure may be achieved in patients with severe renal insufficiency. Advicor and Simcor are both combinations of a statin and niacin see below. If you at a moderate intensity -- meaning you have enough breath to talk but not sing -- for at least 2 ½ hours a week, you can further cut 20% to 30%. Zhu WM, Wu SR. Effects and safety of combined treatment by Xuezhikang and micronized fenofibrate in patients with hyperlipidemia. If you also take cholestyramine, colesevelam, colestipol: these other medicines should be taken at least 1 hour after or 4 hours before you take TriCor. In Japanese, shiatsu means "finger pressure. Simvastatin acid refers to the β-hydroxyacid of simvastatin. Li, J. P. Effect of Xuezhikang Capsule on serum tumor necrosis factor-alpha and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia. best price lexapro and cialis

Lift something too heavy

Colchicine: May enhance the myopathic rhabdomyolysis effect of HMG-CoA Reductase Inhibitors. Colchicine may increase the serum concentration of HMG-CoA Reductase Inhibitors. Simvastatin is a methylated derivative of lovastatin that acts by competitively inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A HMG-CoA reductase, the enzyme that catalyzes the rate-limiting step in cholesterol biosynthesis. In addition to the ability of HMG-CoA reductase inhibitors to decrease levels of high-sensitivity C-reactive protein hsCRP they also possess pleiotropic properties including improved endothelial function, reduced inflammation at the site of the coronary plaque, inhibition of platelet aggregation, and anticoagulant effects de Denus, 2002; Ray, 2005. The clinical observation of the medical treatment for hyperlipidemia with Xuezhikang. While developing and researching lovastatin, Merck scientists synthetically derived a more potent HMG-CoA reductase inhibitor from a fermentation product of A. terreus, which was designated MK-733 later to be named simvastatin. This force can be from a car or bike accident or a direct blow to the spine. A occurs when an injury to the bones in the spine causes them to break and collapse compress on each other, such as from a fall. Simvastatin was developed by and came into medical use in 1992. TG between the two treatment groups were not significantly different. Check with your health care provider before you start, stop, or change the dose of any medicine. Shen MY. Comparison of the effects of Xuezhikang and atorvastatin for treatment of hyperlipidemia. Humpf, H. U. New Monascus metabolites: structure elucidation and toxicological properties studied with immortalized human kidney epithelial cells. Stiripentol: May increase the serum concentration of CYP3A4 Substrates. Management: Use of stiripentol with CYP3A4 substrates that are considered to have a narrow therapeutic index should be avoided due to the increased risk for adverse effects and toxicity. Any CYP3A4 substrate used with stiripentol requires closer monitoring. Guo WC, Feng WJ. Clinical observations of statin alone or combined with unsaturated fatty acids for the treatment of combined hyperlipidemia in elderly people. Patients who are currently tolerating the 80 mg dose who need to be initiated on an interacting drug that is contraindicated or is associated with a dose cap for simvastatin should be switched to an alternative statin with less potential for the drug-drug interaction. Lu WX, Wang JX Zhu JG Xu DS Yang MJ Wang HW Wang RZ Zheng R. Zhibituo capsules in treatment of hyperlipidemia: a multi-centre clinical trial. High-dose simvastatin was associated with a 44 percent increased risk of developing diabetes, while for low-dose simvastatin the increased risk was 28 percent. High-dose atorvastatin was linked to a 37 percent increased diabetes risk, the study found.

Simvastatin warnings

PAZOPanib: HMG-CoA Reductase Inhibitors may enhance the hepatotoxic effect of PAZOPanib. Specifically, the risk for increased serum transaminase concentrations may be increased. Management: Simvastatin is specifically implicated in the interaction. There is a lack of data regarding risk with other statins, but caution appears warranted with any statins. Atorvastatin should be avoided due to P-gp inhibition. Dabigatran Etexilate: Simvastatin may enhance the anticoagulant effect of Dabigatran Etexilate. Management: Consider an alternative HMG-CoA reductase inhibitor statin in patients taking dabigatran who require statin therapy. If used together, monitor patients closely for signs and symptoms of bleeding. Qi MY, Z J X JG. Clinical observation of Xuezhikang on treatment of 112 cases of hypercholesterolemia. Li Y, Min YB Fan XJ. Comparison of the therapeutic effects of Zhibituo and fish oils for treatment of 30 cases of hyperlipidemia. This drug may rarely cause muscle problems which can rarely lead to very serious conditions called and autoimmune myopathy. It may harm them. Xuezhikang capusule in the treatment of hyperlipidemia. Liu, Z. and Zhang, Y. Clinical observation of treatment of hyperlipidemia with Xuezhikang. Your body needs to build new cells, insulate nerves, and produce hormones. Wang AH, Zhang GD. Comparison of the therapeutic effects of Xuezhikang and Lescol for treatment of hyperlipidemia. At a minimum I would recommend that you stop statin therapy immediately and see your doc specifically about statin reaction problems. My doc would not believe that statins cause these issues he has been brainwashed by big Pharma. You should also start taking large CO-Q-10 and L-Carnitine supplements daily as well to help with muscle repair and healing. Almost all my investigations indicate that IF you MUST take a statin drug, it should be NO MORE than 10 mg. per day unless you are taking it after heart surgery etc. Preferably not at all. generic raloxifene us pharmacy

What should i avoid while taking simvastatin

Mitotane: May decrease the serum concentration of CYP3A4 Substrates. Management: Doses of CYP3A4 substrates may need to be adjusted substantially when used in patients being treated with mitotane. Get hit hard in the back. Rarely, changes to the skin, hair, and nails eg, discoloration, dryness, hair loss may occur. Check with your doctor if these effects become bothersome or cause you concern. His shift is at the of a simmering debate in medicine over statins. And it comes at a time when statins -- one of the most commonly prescribed medications in this country, taken by an estimated 1 in 4 middle-aged adults -- may become even more widely used. New guidelines, introduced last November, could push that number to as many as 1 in 2 adults over age 40, according to a recent analysis in the New England Journal of Medicine. Mild to moderate muscle symptoms: Discontinue use until symptoms can be evaluated; evaluate patient for conditions that may increase the risk for muscle symptoms eg, hypothyroidism, reduced renal or hepatic function, rheumatologic disorders such as polymyalgia rheumatica, steroid myopathy, vitamin D deficiency, or primary muscle diseases. Upon resolution, resume the original or lower dose of simvastatin. If muscle symptoms recur, discontinue simvastatin use. After muscle symptom resolution, may then use a low dose of a different statin; gradually increase if tolerated. In the absence of continued statin use, if muscle symptoms or elevated CPK continues after 2 months, consider other causes of muscle symptoms. If determined to be due to another condition aside from statin use, may resume statin therapy at the original dose Stone, 2013. I'm getting a little better. My lean, wasp-waisted hounds are turning into jelly. The dog walker can't walk them every day. They have a life span of about 10 years, but with this life style, they probably will die from a stroke or heart attack in a few years. They try so hard to be amiable about the situation. Sometimes I'm up to walking them around the block. They're so happy, but they stand at a corner and look towards a paved trail that's over a mile away- we used to walk there 3 times a week. I'm a little bit heavier every week- and I was Flaca-skinny. I'm getting where I can dig in my yard-and am finishing a landscape project that I started before the statin hit me. I get so tired- my skin is okay now-but my stomach is bothering me a lot. I have IBS-and an active life helped my digestion. I'm trying to do some exercises-stretches to keep my body from crumpling up. The FDA doesn't care they ruined my life-killed my hounds-make my disabled son cry and fear. Commenting on the study, Dr. Ronald Goldberg, director of the Lipid Disorder Clinic and associate director of the Diabetes Research Institute at the University of Miami, said the researchers "show evidence that statins increased insulin resistance, and that the people who developed diabetes appeared to have less ability to respond to the insulin resistance by making more insulin. Lansheng, G. Comparison of the effects of Xuezhikang and Simvastatin on lipid profile modification in patients with hypercholesterolemia. Beijing Medical University, Dept. If your symptoms do not improve or if they become worse, check with your doctor. Association. FDA web site. American Dietetic Association web site. cardura dosage canada cardura

Use of simvastatin

Amodiaquine: CYP2C8 Inhibitors may increase the serum concentration of Amodiaquine. Peng DY. Observation on the effect of Zhibituo in treating hyperlipidemia. Perry is part of a team of doctors at the University of British Columbia that looks at the evidence for and against drugs. They publish their findings in a free bi-monthly bulletin called Therapeutics Letter. The latest issue urged doctors to be more mindful of side effects when writing for statins. Suspension is administered to patients with severe renal impairment. Deng YM, Meng MK Liao YZ. Clinical observation of Xuezhikang on treatment of elderly patients with primary mixed hyperlipidemia. Lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein HDL "good" cholesterol levels. It is used along with an appropriate diet. It is used in certain patients to reduce the risk of heart attack, stroke, and death due to coronary heart disease. It is also used to reduce the need for medical procedures to open blocked blood vessels. It is also used in certain patients to reduce the risk of heart attack, stroke, blood vessel blockage, or chest pain caused by angina. It may also be used for other conditions as determined by your doctor. Exposure During Pregnancy, Reproductive Toxicology, 106: 439-446, 1996. Yamaguchi, A. Evaluation of photo-mutagenicity and photo-cytotoxicity of food coloring agents. Harvard Medical School: “FDA Changes Safety Information on Statin Drugs. For every 5 to 10 grams that you add to your diet, you can lower your levels by up to 5%. Try to get at least 25 to 30 grams of total fiber a day. Most fruits, vegetables, and oats have both soluble and insoluble fiber. Consult WARNINGS section for dosing related precautions. Fazio, S. Effects of a nutraceutical combination berberine, red yeast rice and policosanols on lipid levels and endothelial function randomized, double-blind, placebo-controlled study. Nutr Metab Cardiovasc. Some medicines, like and progestins, may increase "bad" cholesterol and decrease the "good" cholesterol. Ho, C. Y. Ankaflavin from Monascus-fermented red rice exhibits selective cytotoxic effect and induces cell death on Hep G2 cells. J Agric. Lilja JJ, Neuvonen M, Neuvonen PJ July 2004. Ding W, Zhou Y. Xuezhikang on treatment of hypercholesterolemia. cycrin

Simvastatin uses

Are Lipitor and Zocor the Same Thing? Keep container tightly closed. It is important to talk to your doctor or pharmacist about all prescription, over-the-counter, and herbal products that you take. Be safe with medicines. Read and follow all instructions on the label. Siltuximab: May decrease the serum concentration of CYP3A4 Substrates. LDL cholesterol enough, your doctor may suggest that you also take medicine to help out. Guymer RH, Baird PN, Varsamidis M, Busija L, Dimitrov PN, Aung KZ, Makeyeva GA, Richardson AJ, Lim L, Robman LD 2013. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with or do not feel sick. Jin W, Yang H, Zhang C, et al. A COMPARATIVE STUDY OF XUEZHIKANG AND MEVALOTIN IN TREATMENT OF ESSENTIAL HYPERLIPIDEMIA.

Retrieved 1 December 2012

In fact, one 2003 study showed it worked better than or spinal modification for persistent low back pain -- reducing the need for painkillers by 36%. The Story of Statins. Oxford University Press. It is in the class of medications and works by decreasing the manufacture of cholesterol by the liver. Make sure your concerns are valid before you reject a statin -- their benefits to your are noteworthy. Can Exercise and Diet Lower Your Cholesterol Enough? Li, Y. L. Xuezhikang decreases serum lipoproteina and C-reactive protein concentrations in patients with coronary heart disease. Talk with your doctor or pharmacist if you have questions about effective birth control. Shake the oral suspension well for at least 20 seconds before using it. Use a marked measuring spoon, oral syringe, or medicine cup to measure the right dose. Humpf, H. U. New monascus metabolites with a pyridine structure in red fermented rice. J Agric. Grapefruit Juice: May increase the serum concentration of Simvastatin. Statins block the production of cholesterol in the liver itself. They lower LDL, the "bad" cholesterol, and triglycerides and have a mild effect in raising HDL, the "good" cholesterol. These drugs are the first line of treatment for most people with high cholesterol. Lu, Z. The clinical examinations of Xue-Zhi-Kang in the treatment for hypercholesterolemia. PREGNANCY and BREAST-FEEDING: Do not use simvastatin if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while taking simvastatin. LDL apheresis or alone if such treatments are unavailable. This list is not complete. Other drugs may interact with TriCor, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. You should try to be physically active for 30 minutes every day. money order azulfidine shopping canada

Side effects of simvastatin

Reflexology uses hand, thumb, and finger techniques to stimulate certain areas of the feet. These areas are believed to correspond to different parts of the body. The massage, then, is expected to promote health and well-being. If pregnancy occurs, VYTORIN should be immediately discontinued. Wang DG, Li D Nie ZY. Application of cost-effectiveness analysis in Xuezhikang and pravastatin for the treatment hypercholesterolemia. Niacin is a B-complex vitamin. It's found in food, but it is also available at high doses by prescription. Normally, the makes all the the body needs. But also enters your body from food, such as animal-based foods like milk, eggs, and meat. Use simvastatin as directed by your doctor. Check the label on the medicine for exact dosing instructions. Continued What Drugs Are Used to Treat High Cholesterol? Retrieved 8 December 2016. Experts say another problem is that people may suspect statins when other conditions are really causing their symptoms. The diabetes risk increased with the dosage taken of the statin drugs simvastatin Zocor and atorvastatin Lipitor the researchers said. That was enough to convince him to take his patient, who was suffering from muscle and joint pains, off the medication. If you also take certain other drugs to lower your bile acid-binding resins such as or take this product at least 2 hours before or at least 4 hours after taking these medications. These medications can react with this product, preventing its full absorption. esomeprazole

How should i store simvastatin

Simvastatin is an HMG-CoA reductase inhibitor, also known as a "statin. Ask your health care provider any questions you may have about how to use simvastatin. Ask your health care provider any questions you may have about how to use colchicine. Take VYTORIN 1 time each day in the evening. AUC of total ezetimibe approximately 55%. Yan HD, Guo JH Jia ST. Observations of the short-term effects of Probucol in treatment of hyperlipidemia. Kritchevsky, D. Monascus purpureus-fermented rice red yeast: a natural food product that lowers blood cholesterol in animal models of hypercholesterolemia. Nutrition Res. Your body needs cholesterol for cell structure, nerve function, digestion and many other vital processes. Your body makes its own cholesterol in the liver. Fatty foods and meats also contain cholesterol, which ends up floating around in the bloodstream. Overtime, this extra cholesterol adheres to the walls of arteries, forming a rigid plaque that can restrict blood flow. Sometimes, this restriction is so drastic it can cause heart attacks and strokes, among other serious cardiovascular problems. Ask your healthcare professional how you should dispose of any medicine you do not use. Many types of massage offer benefits beyond simple relaxation. Here are just a few of the health problems that may benefit from massage. Ask your doctor before using massage for any health condition, though. Zhang, T. X. Effects of Xuezhikang and pravastatin on circulating endothelial progenitor cells in patients with essential hypertension. One researcher, David Jenkins MD, has done many studies of the effects of almonds. In a study, he tested 27 men and women with high cholesterol over three months. trazodone

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Simvastatin ingredients

Many herbs can interact with prescription medicines. Always check with your doctor or pharmacist before you take herbal products. Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter. Tell your doctor or dentist that you take colchicine before you receive any medical or dental care, emergency care, or surgery. In those cases, he believes that the benefits of the drug usually outweigh their risks. Xu SG. Analysis of therapeutic effect of Xuezhikang for treatment of primary hypercholesterolemia. bicalutamide price compare

Simvastatin forms and strengths

LDL-C: May be started at 40 mg once daily in the evening; adjust to achieve recommended LDL-C goal. Journal of Nutrition, 2001; vol 131: pp 2275-2279. Corio, R. Studi clinici su Normolip5, integratore alimentare per il controllo del colesterolo. The most common type of massage is Swedish massage therapy. It involves soft, long, kneading strokes, as well as light, rhythmic, tapping strokes, on topmost layers of muscles. This is also combined with movement of the joints. By relieving muscle tension, Swedish therapy can be both relaxing and energizing. And it may even help after an injury.

General information about simvastatin

Lercanidipine: May increase the serum concentration of Simvastatin. Management: Administer lercanidipine in the morning and simvastatin in the evening in patients receiving these drugs in combination. Store simvastatin at room temperature, between 68 and 77 degrees F 20 and 25 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. Keep simvastatin out of the reach of children and away from pets. Li, Y. L. Xuezhikang, an extract of cholestin, protects endothelial function through antiinflammatory and lipid-lowering mechanisms in patients with coronary heart disease. This effect may be worse if you take it with alcohol or certain medicines.

What are the possible side effects of simvastatin

Ezetimibe Zetia works to lower LDL by inhibiting the absorption of cholesterol in the intestines. Vytorin is a drug that combines ezetimibe and a statin. It can decrease total and LDL cholesterol and raise HDL levels. Although ezetimibe may reduce your LDL cholesterol, research studies have not found that it reduces your risk of heart disease. Using these medicines together with simvastatin may increase your risk of muscle injury and could result in kidney problems. Daclatasvir: May increase the serum concentration of HMG-CoA Reductase Inhibitors. VYTORIN and 749 17. Zhao YL, Ouyang HB. Observation on therapeutic effects of Zhibituo for treatment of hyperlipidemia.

Ezetimibe is an antihyperlipidemic agent. It works by reducing the amount of cholesterol that your body absorbs from your diet. Simvastatin is an HMG-CoA reductase inhibitor or "statin. Zhang G, M XY C XB H X M JK W MH. Study of Xuezhikang and atorvastatin on mixed type hyperlipidemia. Some people take along with statins, or -- if their cholesterol isn't too high -- instead of them. There's good evidence that some can help with cholesterol levels. VYTORIN if they are trying to conceive.

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